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Mercedes-Benz GLS-Class MPG

EPA fuel economy for 36 Mercedes-Benz GLS-Class trims sold from 2017 to 2027. Best ever: 21 MPG (2027 GLS450 4matic). Latest model year 2027: 21 MPG combined across 1 trim.

21best combined MPG (2027)
19 / 24city / highway of the best trim
14lowest combined MPG (2017)
11model years rated
$3,920a year to fuel, cheapest 2027 trim at EPA prices

Mercedes-Benz GLS-Class fuel cost calculator

Enter what you pay for fuel and how far you drive in a year. The starting prices are the ones the EPA uses for its own yearly fuel-cost estimates. Every cost on this page updates as you type.

At $5.49 a gallon for premium and 15,000 miles a year, the 2027 Mercedes-Benz GLS-Class costs about $3,920 a year to fuel (GLS450 4matic, 3.0 L, 6 cyl, Hybrid, 21 MPG).

2027 trimEngineTransmissionDriveFuelCombCost/yrvs cheapest
GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium21$3,920cheapest

Cost per year is miles per year divided by the EPA combined rating, times your fuel price; electric vehicles use the EPA's kWh per 100 miles instead. Rounded to the nearest $10. Your prices are kept in this browser only.

Mercedes-Benz GLS-Class MPG by year

YearBest combinedCityHwyBest trim that yearTrims
2027211924GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd1
2026211924GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2025211924GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2024211924GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2023201823GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2022201824GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2021212024GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2020211923GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd2
2019181622GLS450 4matic, 3.0 L, 6 cyl, Auto 9-spd3
2018191722GLS450 4matic, 3.0 L, 6 cyl, Auto 9-spd3
2017191722GLS450 4matic, 3.0 L, 6 cyl, Auto 9-spd3

Every Mercedes-Benz GLS-Class trim

YearTrimEngineTransmissionDriveFuelCityHwyCombCO2 g/miFuel cost/yr
2027GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium192421424$3,920
2026GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium192421428$3,920
2026AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium152017538$4,840
2026GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium142016539$5,150
2026GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium131815585$5,490
2025GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium192421428$3,920
2025GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141916548$5,150
2025AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141815578$5,490
2025GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium131815588$5,490
2024GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium192421428$3,920
2024AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141816564$5,150
2024GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium142016554$5,150
2024GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141916574$5,150
2023GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium182320433$4,120
2023GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium162118499$4,580
2023GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium152017528$4,840
2023AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141916560$5,150
2022GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spd4WDPremium182420433$4,120
2022GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium162118498$4,580
2022GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium142017533$4,840
2022AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141815571$5,490
2021GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spd4WDPremium202421414$3,920
2021GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium162118491$4,580
2021AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium141816559$5,150
2021GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium151916539$5,150
2020GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spd4WDPremium192321429$3,920
2020GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium162118487$4,580
2019GLS450 4matic3.0 L, 6 cylAuto 9-spd4WDPremium162218488$4,580
2019GLS550 4matic4.7 L, 8 cylAuto 9-spd4WDPremium141916572$5,150
2019AMG GLS635.5 L, 8 cylAuto 7-spd4WDPremium131815601$5,490
2018GLS450 4matic3.0 L, 6 cylAuto 9-spd4WDPremium172219477$4,330
2018GLS550 4matic4.7 L, 8 cylAuto 9-spd4WDPremium141916556$5,150
2018AMG GLS635.5 L, 8 cylAuto 7-spd4WDPremium131815591$5,490
2017GLS450 4matic3.0 L, 6 cylAuto 9-spd4WDPremium172219477$4,330
2017GLS550 4matic4.7 L, 8 cylAuto 9-spd4WDPremium141816562$5,150
2017AMG GLS635.5 L, 8 cylAuto 7-spd4WDPremium131714615$5,880

CO2 is tailpipe grams per mile from the EPA test. Fuel cost per year uses the prices and miles in the calculator above (the EPA's own prices and 15,000 miles a year until you change them); blank when the fuel has no price here (hydrogen, natural gas).

Compare with other 2027 Standard Sport Utility Vehicle 4WD

VehicleCombinedCityHwy
2027 BMW iX3 50 xDrive (20 inch Summer Tires)118125110
2027 Lucid Gravity Touring w/20F21R wheels111115106
2027 Volvo EX60 P10 AWD electric110118102
2027 Rivian R2 Performance AWD (21in)10511496
2027 Audi Q6 Sportback e-tron quattro10411097
2027 Cadillac OPTIQ AWD 11kW Charger9911088

All Standard Sport Utility Vehicle 4WD ranked by MPG

Questions people ask

What is the best MPG for a Mercedes-Benz GLS-Class?

The most efficient Mercedes-Benz GLS-Class the EPA has rated is the 2027 GLS450 4matic at 21 MPG combined (19 city, 24 highway).

What MPG does the 2027 Mercedes-Benz GLS-Class get?

Every 2027 Mercedes-Benz GLS-Class trim is rated 21 MPG combined.

Which Mercedes-Benz GLS-Class has the worst fuel economy?

The 2017 AMG GLS63 is the lowest rated at 14 MPG combined.

How much does it cost to fuel a Mercedes-Benz GLS-Class for a year?

At $5.49 a gallon for premium and 15,000 miles a year, the 2027 Mercedes-Benz GLS-Class costs about $3,920 a year to fuel (GLS450 4matic, 3.0 L, 6 cyl, Hybrid, 21 MPG).

More from Mercedes-Benz: every Mercedes-Benz model. Fuel types on this model: Premium. EPA classes: Standard Sport Utility Vehicle 4WD.