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Mercedes-Benz GLS-Class MPG

EPA fuel economy for 35 Mercedes-Benz GLS-Class trims sold from 2017 to 2026. Best ever: 21 MPG (2026 GLS450 4matic). Latest model year 2026: 15 to 21 MPG combined across 4 trims.

21best combined MPG (2026)
19 / 24city / highway of the best trim
14lowest combined MPG (2017)
10model years rated
$3,690a year to fuel, cheapest 2026 trim at EPA prices

Mercedes-Benz GLS-Class fuel cost calculator

Enter what you pay for fuel and how far you drive in a year. The starting prices are the ones the EPA uses for its own yearly fuel-cost estimates. Every cost on this page updates as you type.

At $5.16 a gallon for premium and 15,000 miles a year, the cheapest 2026 Mercedes-Benz GLS-Class to fuel is the GLS450 4matic, 3.0 L, 6 cyl, Hybrid (21 MPG) at $3,690 a year. The GLS600 4matic Maybach, 4.0 L, 8 cyl, Hybrid (15 MPG) costs $5,160, so the thriftier trim saves $1,470 a year and $7,350 over five years.

2026 trimEngineTransmissionDriveFuelCombCost/yrvs cheapest
GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium21$3,690cheapest
AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium17$4,550+$870
GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium16$4,840+$1,150
GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium15$5,160+$1,470

Cost per year is miles per year divided by the EPA combined rating, times your fuel price; electric vehicles use the EPA's kWh per 100 miles instead. Rounded to the nearest $10. Your prices are kept in this browser only.

Mercedes-Benz GLS-Class MPG by year

YearBest combinedCityHwyBest trim that yearTrims
2026211924GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2025211924GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2024211924GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2023201823GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2022201824GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2021212024GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd4
2020211923GLS450 4matic, 3.0 L, 6 cyl, Hybrid, Auto 9-spd2
2019181622GLS450 4matic, 3.0 L, 6 cyl, Auto 9-spd3
2018191722GLS450 4matic, 3.0 L, 6 cyl, Auto 9-spd3
2017191722GLS450 4matic, 3.0 L, 6 cyl, Auto 9-spd3

Every Mercedes-Benz GLS-Class trim

YearTrimEngineTransmissionDriveFuelCityHwyCombCO2 g/miFuel cost/yr
2026GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium192421428$3,690
2026AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium152017538$4,550
2026GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium142016539$4,840
2026GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium131815585$5,160
2025GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium192421428$3,690
2025GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141916548$4,840
2025AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141815578$5,160
2025GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium131815588$5,160
2024GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium192421428$3,690
2024AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141816564$4,840
2024GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium142016554$4,840
2024GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141916574$4,840
2023GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spdAWDPremium182320433$3,870
2023GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium162118499$4,300
2023GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium152017528$4,550
2023AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141916560$4,840
2022GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spd4WDPremium182420433$3,870
2022GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium162118498$4,300
2022GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium142017533$4,550
2022AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spdAWDPremium141815571$5,160
2021GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spd4WDPremium202421414$3,690
2021GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium162118491$4,300
2021AMG GLS63 4matic Plus4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium141816559$4,840
2021GLS600 4matic Maybach4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium151916539$4,840
2020GLS450 4matic3.0 L, 6 cyl, HybridAuto 9-spd4WDPremium192321429$3,690
2020GLS580 4matic4.0 L, 8 cyl, HybridAuto 9-spd4WDPremium162118487$4,300
2019GLS450 4matic3.0 L, 6 cylAuto 9-spd4WDPremium162218488$4,300
2019GLS550 4matic4.7 L, 8 cylAuto 9-spd4WDPremium141916572$4,840
2019AMG GLS635.5 L, 8 cylAuto 7-spd4WDPremium131815601$5,160
2018GLS450 4matic3.0 L, 6 cylAuto 9-spd4WDPremium172219477$4,070
2018GLS550 4matic4.7 L, 8 cylAuto 9-spd4WDPremium141916556$4,840
2018AMG GLS635.5 L, 8 cylAuto 7-spd4WDPremium131815591$5,160
2017GLS450 4matic3.0 L, 6 cylAuto 9-spd4WDPremium172219477$4,070
2017GLS550 4matic4.7 L, 8 cylAuto 9-spd4WDPremium141816562$4,840
2017AMG GLS635.5 L, 8 cylAuto 7-spd4WDPremium131714615$5,530

CO2 is tailpipe grams per mile from the EPA test. Fuel cost per year uses the prices and miles in the calculator above (the EPA's own prices and 15,000 miles a year until you change them); blank when the fuel has no price here (hydrogen, natural gas).

Compare with other 2026 Standard Sport Utility Vehicle 4WD

VehicleCombinedCityHwy
2026 Lucid Gravity Touring w/20F21R wheels111115106
2026 Tesla Model X10511099
2026 Cadillac OPTIQ AWD (11 kW Charger)9911088
2026 Honda Prologue AWD Touring9910890
2026 Audi Q4 55 e-tron quattro9710589
2026 BMW iX xDrive60 (20 inch Wheels)979994

All Standard Sport Utility Vehicle 4WD ranked by MPG

Questions people ask

What is the best MPG for a Mercedes-Benz GLS-Class?

The most efficient Mercedes-Benz GLS-Class the EPA has rated is the 2026 GLS450 4matic at 21 MPG combined (19 city, 24 highway).

What MPG does the 2026 Mercedes-Benz GLS-Class get?

2026 Mercedes-Benz GLS-Class trims range from 15 to 21 MPG combined, depending on engine, transmission and drivetrain.

Which Mercedes-Benz GLS-Class has the worst fuel economy?

The 2017 AMG GLS63 is the lowest rated at 14 MPG combined.

How much does it cost to fuel a Mercedes-Benz GLS-Class for a year?

At $5.16 a gallon for premium and 15,000 miles a year, the cheapest 2026 Mercedes-Benz GLS-Class to fuel is the GLS450 4matic, 3.0 L, 6 cyl, Hybrid (21 MPG) at $3,690 a year. The GLS600 4matic Maybach, 4.0 L, 8 cyl, Hybrid (15 MPG) costs $5,160, so the thriftier trim saves $1,470 a year and $7,350 over five years.

More from Mercedes-Benz: every Mercedes-Benz model. Fuel types on this model: Premium. EPA classes: Standard Sport Utility Vehicle 4WD.